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Thursday, August 23rd, 2012
10:19 pm
Фильмы 2012 скачать

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5:38 pm
Оренбургские секс знакомства

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Сайт знакомств без регистрации в казани с номерами телефонов Скайп интим знакомства знакомства без регистрации в казахстане Бдсм знакомства в набережных челнах Секс знакомства ульяновск Знакомства для секса без регистрации и смс ростов-на-дону Знакомства ленинградская область город Сайт знакомств богатые девушки ищут мужчин Знакомства для секса без обязательств
Tuesday, August 17th, 2010
12:40 pm
Американцы успешно испытали принципиально новые лекарства от гепатита С
В США успешно завершились исследования принципиально новых препаратов от гепатита С, сообщает Nature. Фармацевтические компании Merck и Vertex Pharmaceuticals заявили об окончании поздней фазы клинических испытаний боцепревира и телапревира соответственно.

В настоящее время для лечения гепатита С используются неспецифические противовирусные лекарства в комбинации с интерфероном-α. Несмотря на то, что большинство больных выздоравливает после годичного курса этих лекарств, используемые препараты вызывают ряд серьезных побочных эффектов, в том числе анемию, простудные заболевания, депрессию.

Оба новых препарата относятся к группе ингибиторов протеазы. Они блокируют действие этого фермента, в результате чего нарушается процесс синтеза вирусных белков. По результатам клинических испытаний, у двух третей больных гепатитом С после 48 недель приема боцепревира в комбинации с традиционной схемой лечения концентрации вирусной РНК в крови снизилась до лабораторно неопределяемого уровня. При этом некоторые пациенты успешно завершили курс через 28-36 недель после начала лечения.

Телапревир также испытывался в комбинации со стандартной схемой лечения. По результатам исследований, значительное снижение концентрации вирусной РНК наблюдалось у 72 процентов участников после 24 недель использования нового препарата. Наиболее высокие шансы выздоровления были зафиксированы в группе пациентов, действие нового лекарства у которых начало проявляться на 4-12 неделе лечения.

Merck и Vertex планируют подать документы на регистрацию разработанных препаратов от гепатита С в Управление по контролю за продуктами и лекарствами США (FDA) до конца 2010 года. Фармкомпании рассчитывают получить одобрение надзорных органов к середине 2011 года. По словам экспертов, в случае выхода на рынок объем продаж новых лекарств может достигнуть 15 миллиардов долларов к 2017 году.

Sunday, November 25th, 2007
4:54 pm
It is cold and wet today~
I am feeling lazy today. We were supposed to have a young man come rake leaves today and he didn't show up - can't blame him because it is drizzly and cold. He knocked on our door yesterday afternoon and offered.. Jim said he was about 10 years old and his parent/adult was driving him in a mini-van... $25.00 for our front yard(worth it). Jim said okay... he is probably needing Christmas money. Said he'd be back today about the same time. A no show LOL. WE HAVE A LOT OF LEAVES TOO! But like I said it is cold and wet.

We'll give him another chance before we rake our leaves. (we? LOL I mean Jim)

I'm sure our neighbors to the right of us would really like us to rake... they have raked several times already. Why? Let them all fall first. I personally love them. I love walking in them.

Didn't get the boys this weekend and Tonya was supposed to bring Shelby by for her birthday present... but didn't show either.

I think tonight will be a early to bed... I am cold and sleepy. I am dreading work tomorrow... yuck!

Friday is my liver doc appt... I was supposed to take my last shot this past Friday and skipped it. I am done for awhile... I need a break!

Well gonna close and check e-mail.

(I know this was a boring post but just felt I needed to post something)

Current Mood: bored
Tuesday, June 12th, 2007
9:58 pm
New Study

An interesting development with the new alpha-interferon they've been testing.

I have read about this drug a few times, but I can't remember if any of the studies are with HCV1's. I know one of them was a HCV2 group and they were like SVR'd for ever.

Just thought you might appreciate it. Read carefully cause it can get a little confusing.
Thursday, March 15th, 2007
7:30 am
HCV Transmission potentially possible through saliva?
I'm not quite sure what to think of this abstract, but I just thought some of you would want to know, they are wondering about it.


Please don't flame the messenger ;-). I just like to try to keep people informed, and as with anything in science and medicine, nothing is definite.
Friday, February 2nd, 2007
5:22 pm
Have any of you had a problem with headaches during treatment? I've been having migraine-like headaches for about a week.

I talked to my gastro doc; he says if they don't abate, he may discontinue treatment and that severe headaches are not common side effects. He also suggested talking to my regular doc, so I have an appointment with her on Monday.

Any help would be appreciated.

Tuesday, January 23rd, 2007
1:53 am
Just greetings
Hey gang,
Just wanted to take a moment to introduce myself. I'm 32, Hep C type 1 positive, currently in my second attempt at treatment.
things are going okay, and at the moment, I'm at zero load, though who knows if that will continue (we all know what this virus is like).
Looking forward to getting to know you guys. I don't know why it took me so long to search for group with this topic, duh!
Monday, January 15th, 2007
5:51 pm
Does anyone know
if there is an auto-injector available for any of the hcv injectables? Like an Epi Pen??

Saturday, December 30th, 2006
8:29 pm
hep c & autoimmune disease & advice
Hi all. My name is Tess and I'm 22. Just a few days ago, I was told that my third annual STD blood tests came back Hep C positive (the qualitative/antibodies test if I understand this right). My gyno (who recently added HCV to her testing) referred me to get more extensive testing (the quantitative one I believe) to see where the disease is. My appointment with my GP is next week.

This news is completely crushing for me, as another health problem is the polar opposite of what I need right now. The past three months I have been recovering well from a surgery to cure Conn's Syndrome (caused by a tumorous, cyst-producing, hemmoraging left adrenal gland, which is now gone). In addition, I have two autoimmune diseases that have developed over the past 5 or 6 years - Hashimoto's Thyroiditis and lichen planus (in my gums). I was tired of these problems already... now there's more on my plate.

Previous to this week's news, I had been trying to figure out a connection between my various medical conditions. I see an endocrinologist, and she has been great in helping me get my thyroid back on track and she helped me find a surgeon who was willing to remove my adrenal gland. But neither she nor my other doctors have ever sought to put what I'm convinced is a puzzle together. Has anyone here had autoimmune problems with their HCV? Is anyone familiar with evidence supporting these ideas?

In addition, I have been trying to deal with the feelings of anger I have been experiencing - toward myself for putting loved ones at risk because I didn't know and toward the universe. I also feel ashamed, and I don't want many people to know. I know that sharing health issues is a very personal decision, but any advice on breaking news such as "I have HCV" would be appreciated. I am also terrified of future relationships, as I don't want to break news to someone that I have something they could catch potentially.
Friday, October 13th, 2006
11:30 am
Hey everyone

Hopefully this won’t come across as advertising, but I was invited to beta test this site you all might want to check out. It’s called www.lovehealz.com and is basically a mix between Myspace and eHarmony specifically for people with Hepatitis C and other illnesses. They said they are going to be donating millions of dollars to charities like the International AIDS Vaccine Initiative and the American Social Health Association! That’s really why I wanted to post here.

It seems like they’re supporting a really great cause and could really use some additional opinions to make it work.

Here’s the beta code to sign up: RFBETA06
Hope to see you there!

Thursday, September 28th, 2006
8:20 am
i'm not sure which of these irritate me more...THIS or THIS.

and pam anderson, we won't even GO there.

what about the thousands of people who truly DO suffer in silence? how about taking these stupid drugs for 5 years and NOT clearing? ...and the 17,000 people on the transplant list?!?!

but yet, he will go on Oprah - let me rephrase, he will be *approved* to talk to Oprah because he is Steven Tyler.

Steve and Pam, hardly the representative voices i would choose.


Current Mood: irritated
Friday, July 21st, 2006
7:19 pm
Hi, I'm new here. I have some questions about some things, and I thought people here might be able to answer some of them. (Pardon any typos, I'm typing in the dark on a laptop and have typing dyslexia :)

In 1997, I donated blood at a blood drive at University at Buffalo. A couple of months after, I got a letter from the ARC saying that I tested positive for Hep C. I don't have the letter anymore, but I remember it saying something about me having antibodies to HCV in my bloodstream. I went to a doctor and had some kind of blood test and they said I didn't have Hep C. I'm thinking, OK, maybe the ARC got my blood mixed up with someone else's.

Eight years later, I try donating blood again through a different blood donating agency in Florida. Same thing happened; I get a letter saying I have Hep C antibodies in my blood, and that I need to be tested to make sure I don't have it. Now I'm worried.

1) How could I have gotten exposed to it? I never tried IV drugs, never snorted coke, at that time I wasn't a healthcare worker, and in 1997 I hadn't even had sex yet. I did have a manicure once, sometime between 1995-1996, but the place seemed clean and I though they used clean instruments.

2) Why do I still have antibodies so long after I would have been exposed to it? Does that mean I could still have the virus but my body is keeping it in check? Could the blood test I had in 1997 have been wrong and I actually had Hep C and just let it run rampant for close to a decade?

Read more...Collapse )

Any information would be highly appreciated.
Tuesday, April 11th, 2006
12:37 pm
The Treatment - Strange Side Effects
This is being posted in my own journal for my friends who might have some medical knowedge, and also x-posted in the Hep-C communities.

I've been having some very strange problems with my teeth and gums while on the treatment. Several times after taking my shots, I've felt like my teeth have been re-arranged during my sleep. To the point where my bite is completely out of whack. I've made several posts about it as the treatment has progressed.

Recently (since increasing the frequency of my shots), I've also noticed a marked change in my gums. At first it was a difference that my tongue felt inside my teeth. It was like my gums were retreating and there was more of my teeth exposed.

There's no pain and I go to the dentist every six months religiously. Always have. Always will. So I haven't really worried about it.

But the amount of tooth that my tongue feels has become alarming. I did a close inspection in the mirror this morning and completely freaked out! My gums are shortening and I have exposed roots on nearly all my top teeth. We're talking 1/4" on the front four teeth!!

The bottom ones aren't nearly as severe, although my gums have thinned so much that there is one root that is visible down near my jaw.

Holy shit! Has anyone ever heard of this happening due to the treatment?
Saturday, April 8th, 2006
9:05 pm
Philosophy of a Liver Transplant
During the course of my Masters work this term, I read an interview of Francisco Varela, Chilean biologist and philosopher (who pursued research characterized as 'experimental epistemology'), by Bernhard Poerksen, called "Truth is What Works: A Conversation on Cognitive Science, Buddhism, the Inseparability of Subject and Object and the Exaggerations of Constructivism" (available only, it seems, through Project Muse). Varela's views resonated with many of my own and I sought further information about him and his work.

I was surprised to learn that Varela had battled with and eventually died (28 May 2001) from complications arising from HCV. He had also had a liver transplant and wrote an essay about his experiences, called "Intimate Distances: Fragments for a Phenomenology of Organ Transplant" that I thought might be of interest to some folks here. I felt a profound sense of awe and affinity reading this, though I've never had an organ transplant. I am grateful on a daily basis that I am one of the lucky ones: two and a half years after my treatment and HCV is still undetectable.

It's a chunky academic read in many places, but it is grounded in often poetic speculation about his own circumstances as he goes through the various stages of the transplant process. He asks questions within his own experience that reach beyond himself. I was inspired and I hope others who live with HCV find inspiration in his words.
Wednesday, March 22nd, 2006
12:02 pm
I just picked up today's Interferon shot from the pharmacy, but it's different this time. Usually I get one fully-loaded injectable needle - a Redipen. This time I got two vials (one powder and one liquid) and two long-ass needles. What do I do with that?

Anybody who's been on this treatment ever used the dual vial/dual needle system? Any idea what I'm supposed to do?


Monday, February 13th, 2006
11:02 am
HCV Journal looking for stories
The International Journal of Drug Policy is inviting contributions to a forthcoming special issue on responses to the hepatitis epidemic among IDU s. Guest editors Samuel R. Friedman, Walter Cavalieri, Nick Crofts, Annie Madden, Avril Taylor, and Nick Walsh are particularly interested in including personal articles, stories, and analytical articles based on the direct experiences (including collective efforts to improve things) of people affected by hepatitis C including current injecting drug users and former injecting drug users. These articles might cover issues such as personal stories about living with hepatitis C; facing discrimination and stigma; experiences trying to avoid getting hepatitis C in community settings and/or in prisons; pregnancy; childbirth and parenting when you
have hepatitis C; difficulties of gaining access to treatment for the disease; and what it is like to undergo hepatitis C treatment.

The editors will offer assistance to anyone who has such person experience and would like help writing an abstract. Please contact Thus we especially seek to include articles by those with experience in these areas. If you are co-editor Annie Madden at AnnieM@aivl.org.au for assistance, or Sam Friedman at friedman@ndri.org for more information.

The deadline for submission of outline abstracts is April 1, 2006.
Tuesday, January 24th, 2006
12:27 am
I just got invoices for 2 tests done at the end of August. It seems that my insurance company doesn't pay for the genotype and the Heptimax tests. Has anyone else had problems with their insurance companies not covering the tests?? I haven't had a chance to call the insurance company yet - that's on my list for tomorrow.

Oh, yeah...I'm Kate and I was diagnosed with HCV in July. Chances are more than good that I got it while being treated for Guillain-Barre Syndrome. Treatment for GBS is plasmapheresis (plasma exchange done with a dialysis machine).

GBS is a neurological syndrome that is usually triggered by a virus. The antibodies created to fight the virus don't shut off and begin attacking the myelin sheath on the nerves. Kinda like something munching on the insulation of a wire. Anyway, it can be mild or severe. It's painful - since the insulation is compromised, nerves sort of short circuit. It can also cause paralysis. Fortunately, GBS is fairly rare - 1 or 2 in 100,000 and recovery, while lengthy (2+ years), is around 85%.

If you want to know more, just let me know.

Current Mood: annoyed
Wednesday, January 4th, 2006
5:42 pm
Hair loss question
I am in week 20-something of my treatment. Nearly halfway through. (Yay me!!)

In the last week or so my hair has started thinning noticeably and falling out in clumps. My hair has always been fine and thin, but now when you look at me you don't see hair around my head, you see scalp. At least that's what I see when I look in the mirror. I'm not quite sure what to do now.

My hair has always been shoulder-length. click here for pre-treatment pictures:Collapse )

Here is my question: Would it do any good for me to chop off my hair to a shorter length? Will the decrease in weight help stop it from falling out? Should I go ahead and buzz it? Should I just leave it alone?

I'm at a loss. A complete and total loss. I knew this was a possibility but I have been in denial. Now that it's really here, what do I do?

I guess that was more than one question, huh?

Thanks for your help!!
Tuesday, November 15th, 2005
10:20 pm
Hey all, I'm new here. I've been trying to find information, and while webmd, CDC, UNOS, etc. are giving me some good basics, I'm hoping to get in contact with others with personal experience.

Within the past month, my father was diagnosed with early stage liver cancer, cirrhosis, and Hepatitus C. His doctors have decided that a transplant is the best course of treatment. I want to get myself tested to find if I would be a match for an adult-to-adult living donor transplant. But I don't want my parents to know just yet, as I don't think they would agree with it.

I don't know if I need to contact his doctors, or someone local to me. (I'm 120 miles away from where they live.) I don't know what it entails, not that it makes a lot of difference. Anything you guys can share would be much appreciated; I'm coping with this by learning all that I can.
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